High-Throughput Screening Past Projects

Designed and constructed Alpha models of a highly sensitive Fluorescence-Polarization based compound analysis system.  Instruments were successfully shipped to partner sites throughout the US.  Instruments based on this design are now being offered as a commercial product.

Designed an optical readout system to couple to a MEMS-based compound screening system.

Designed and constructed prototypes of multi-color fluorescence imaging systems for ultra-high density microarrays (3 micron samples).

Designed and implemented automated sample handling for microarray imaging systems.  Up to 96 individual microarrays may be automatically imaged without operator intervention.

Co-invented, designed and built the core technology for Illumina's array-of-arrays platform.

Designed system integration and automation of high-throughput DNA sequencing chemistries with large-scale 96 and 384-well sample plate handling and storage for automated sequence finishing.

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